Ketamine Therapy to Treat Depression and Anxiety

Ketamine Infusion Therapy conveniently located in Philadelphia

At Mindstream Medicine, we recognize that even with compliance and dedication, traditional medications and talk therapy alone may not provide relief for all patients suffering from depression, anxiety and other mental health conditions. We are here to help.

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Ketamine Philadelphia

What is Psychedelic Assisted Therapy?

As proponents of Psychedelic Medicine, we believe that medications, such as ketamine, hold the potential to help some people break free from the crushing stress of chronic mental health conditions. While Psychedelic Medicine may provide some patients with a breakthrough in their struggle to improve their mood or stress levels, the effects can last longer and be more effective if they are incorporated with talk therapy.
Mindstream Medicine offers psychedelic assisted therapy, by method of ketamine infusion, in our Philadelphia location. We look forward to collaborating with your mental health practitioner to help bring your therapy to the next level, and if you are not currently in therapy, we can connect you with a network of providers who are interested in assisting you on this journey.
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What is Ketamine?

History of Ketamine

While initially developed as an anesthesia agent in the 1960’s, ketamine has more recently become recognized as a medication that can be used in the treatment of multiple mental health disorders (1). Ketamine functions as an anesthesia agent by blocking incoming sensory information to the brain. It is unique among other anesthesia medicines because it does not slow down the brain or stop a patient from breathing on their own.

How Does Ketamine Work?

Because less sensory information is coming into the brain, the nerve cells there create new branches to reach out for new connections and information.  The ability to build new pathways in the brain after a ketamine experience is known as “neuroplasticity,” and this is the phenomenon that is believed to be responsible for the ability to build new neural networks, or streams, as we integrate that experience into our therapeutic relationship with a mental healthcare provider (2).

Even a brief break from the constant influx of sensory input and the sometimes disorganized or harmful cognitive patterns that we live with every day can provide an opportunity to rethink the way we appreciate our own existence and how we interact with the people around us.  This is how one may be able to “break free” from the deeply entrenched crushing burden of depression, anxiety, and possibly other soon-to-be indicated medication-resistant mental health disorders.  A recent seminal publication in the New England Journal of Medicine further supports the effectiveness and safety of infusion ketamine in the management of treatment-resistant major depression (3).

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What Happens During a Ketamine Treatment Session?

While some mental health providers perform psychotherapy after administering ketamine orally or under the tongue, we provide ketamine either via an intramuscular injection or through an intravenous infusion drip, which results in a deeper psychedelic experience. This is typically done with a planned 6 sessions delivered over a 3-6 week period, with each session lasting for several hours.  The patient will typically wear a headset playing peaceful music or soundscape, along with a light-blocking eye mask.

No talk therapy takes place while the patient is under the influence of the medication, so that they may focus on the experience itself.  The Patient is closely monitored by a trained medical professional inside the treatment room, usually by the medical director, at all times.  This is to ensure that any potentially rare negative reactions from the medication can be handled quickly and appropriately by our board-certified emergency medicine physician, Dr. Husted.  Unlike some other ketamine clinics, no one is left alone by him/herself during the entire process.

What Happens After a Ketamine Treatment Session?

It is in the days following the session that the patient will return to their therapist to talk about their experience and how it relates to their goals in therapy, a process known as integration.


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**Initial phone consultation and in-person medical examination with Dr. Evan Husted, M.D., MPH are FREE.  You will only pay once you have decided to proceed with treatment after you have been medically cleared and that all of your questions have been answered.**

Ketamine Therapy Cost at Mindstream Medicine Philadelphia

$450 for each intravenous infusion session OR

$400 for each intramuscular injection session OR

6-Session Package: $2,250 intramuscular/$2,600 IV infusions